Human inner kinetochore structure reveals mechanism for binding DNA during mitosis - MRC Laboratory of Molecular Biology
cam.ac.uk
Human inner kinetochore structure reveals mechanism for binding DNA during mitosis - MRC Laboratory of Molecular Biology
In solving the structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome, David Barford’s group in the LMB’s Structural Studies Division has revealed how the complex recognises centromeric DNA and functions as a load-bearing element during chromosome segregation.
Apr 19, 2022
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